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Iprasense's high-throughput Cytonote Cell Counter, up to 96 cell cultures can be monitored in parallel and in real time. Like the company's previous-generation cell counter, the new product provides very accurate statistics on cell viability and requires no pre-screening treatment.
The product is the third in a lineup that leverages a lensless imaging technology developed at Leti, a CEA Tech institute. The technology increases the visual field by a factor of ten over traditional microscope (24 sq. mm). Light emitted by a LED is diffracted by the cells being observed, creating a hologram recorded by a CMOS sensor. The images are then reconstructed from the diffraction patterns using holographic algorithms and displayed on a screen. A signal processing technique is also used to determine whether cells are viable or not.
Samples from 3 ml to 13 ml are placed on a 96-well plate, allowing labs to test the effects of 96 substances on the same cell culture, for example. This capability makes the product ideal for antibiotic sensitivity tests, high-throughput cellular screening for drug discovery, or to monitor the effectiveness of a therapy.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.